DAP Antibody, FITC conjugated

Code CSB-PA01034C0Rb
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) DAP Polyclonal antibody
Uniprot No.
Target Names
DAP
Alternative Names
DAP 1 antibody; Dap antibody; DAP-1 antibody; DAP1_HUMAN antibody; Death associated protein 1 antibody; Death associated protein antibody; Death-associated protein 1 antibody; MGC99796 antibody; OTTHUMP00000161670 antibody; OTTHUMP00000221331 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Death-associated protein 1 protein (2-102AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
FITC
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Negative regulator of autophagy. Involved in mediating interferon-gamma-induced cell death.
Gene References into Functions
  1. DAP1 may have an important role in cell adhesion, migration and growth in the context of breast cancer and has significant associations with the apoptosis pathway. PMID: 25530065
  2. DAP1 was found to be correlated with disease progression and long-term survival of the colorectal patients. DAP1 is also a pivotal regulator of the growth and apoptosis and cellular response to chemotherapy agents. PMID: 24270644
  3. This study demonstrates an inverse association between DAP1 mRNA levels and tumour stage and clinical outcome in breast cancer PMID: 22798505
  4. Mapping of the phosphorylation sites and analysis of phosphorylation mutants indicated that DAP1 is functionally silenced in growing cells through mTOR-dependent phosphorylations on Ser3 and Ser51 PMID: 20537536
Database Links

HGNC: 2672

OMIM: 600954

KEGG: hsa:1611

STRING: 9606.ENSP00000230895

UniGene: Hs.75189

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