DAP Antibody, FITC conjugated

Datasheet

Code	CSB-PA01034C0Rb
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) DAP Polyclonal antibody

Uniprot No.

P51397

Target Names

DAP

Alternative Names

DAP 1 antibody; Dap antibody; DAP-1 antibody; DAP1_HUMAN antibody; Death associated protein 1 antibody; Death associated protein antibody; Death-associated protein 1 antibody; MGC99796 antibody; OTTHUMP00000161670 antibody; OTTHUMP00000221331 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Death-associated protein 1 protein (2-102AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

FITC

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Negative regulator of autophagy. Involved in mediating interferon-gamma-induced cell death.

Gene References into Functions

DAP1 may have an important role in cell adhesion, migration and growth in the context of breast cancer and has significant associations with the apoptosis pathway. PMID: 25530065
DAP1 was found to be correlated with disease progression and long-term survival of the colorectal patients. DAP1 is also a pivotal regulator of the growth and apoptosis and cellular response to chemotherapy agents. PMID: 24270644
This study demonstrates an inverse association between DAP1 mRNA levels and tumour stage and clinical outcome in breast cancer PMID: 22798505
Mapping of the phosphorylation sites and analysis of phosphorylation mutants indicated that DAP1 is functionally silenced in growing cells through mTOR-dependent phosphorylations on Ser3 and Ser51 PMID: 20537536

Database Links

HGNC: 2672

OMIM: 600954

KEGG: hsa:1611

STRING: 9606.ENSP00000230895

UniGene: Hs.75189

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